ImTracker MULTI COVID-19 Viral Variant Neutralization Test is a colorimetric serological enzyme-linked immunosorbent assay (ELISA) intended for the semi-quantitative detection of neutralizing antibodies that block binding of the host receptor Angiotensin Converting Enzyme-2 (ACE2) to six viral variants of  the Receptor Binding Domain (RBD) of SARS-CoV-2. The detection reagent, ACE2-Horse Radish Peroxidase (HRP) conjugate, catalyzes the conversion of chromogenic substrates (e.g., TMB) into colored products, whose absorbance can be measured at A450.

Viral variant RBDs included in the test: Wu-hu-1 (ancestral); Beta; Gamma; Delta; Omicron BA.1; Omicron BA.2.

(Omicron BA.4/5 RBD is available for purchase separately).

The test is suitable for plasma or serum samples and each kit holds reagents to test up to 60 samples, in duplicate, against 6 RBD viral variants.

The test can be used to identify individuals with an adaptive immune response to the common SARS-CoV-2 strains of concern, indicating prior infection, or for evaluating vaccine responses. The capacity of the detected antibodies to inhibit binding of viral RBD to the SARS-CoV-2 cell surface receptor (ACE2), indicates their potential to reduce or block infection by SARS-CoV-2.

CATALOGUE #:

GY-Im-001 (CE Mark IVD Product)

GY-Im-RUO (Research Use Only) Includes the latest variants! Please enquire for details.